Severe Psoriasis Presenting in 3 Year Old Child With Nail Dystrophy Next Steps in Dermatology Topical Management of Plaque PsoriasisA Review and Case Series Discussion with Focus on Aryl Hydrocarbon Receptor Modulation JCAD The Journal of Clinical and Aesthetic Dermatology Orchestrated Cytokines Mediated by Biologics in Psoriasis and Its Mechanisms of Action Many treatment guidelines for psoriasis rely heavily on body surface area (BSA) involvement to determine disease severity and eligibility for systemic therapies like biologics. Traditionally, patients with less than 10% BSA involvementespecially