5 6) By contrast, latency I Burkitt B cells were particularly vulnerable to ferroptosis induction by blockade of either cystine import, glutathione synthesis or glutathione peroxidase 4 (GPX4). Eric also found roles for Frontiers Glutathione peroxidase 4 as an emerging therapeutic target in osteoarthritis: focus on ferroptosis Chicken or Egg? Mitochondrial Phospholipids and Oxidative Stress in Disuse Induced Skeletal Muscle Atrophy Edwin R. Miranda, Justin L. Shahtout, Katsuhiko Funai, 2023 Glutathione peroxidase 4: a new player in neurodegeneration? Molecular Psychiatry