Glutathione Related Enzymes and Proteins: A Review Leucovorin (Folinic Acid) The Rescue Drug! Pearl:Leucovorin (Folinic Acid) is Methotrexate's antidote. It is the reduced form of folate that can bypass the enzyme dihydrofolate reductase (which Methotrexate inhibits). Application: It Open Veterinary Journal Frontiers Nitazoxanide mitigates methotrexate hepatotoxicity in rats: role in inhibiting apoptosis and regulating endoplasmic reticulum stress
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glutathione and methotrexate Methotrexate works remotely, from the gut: Cell Host & Microbe