Brain health depends on balance. From energy production to antioxidant protection and immune regulation, multiple systems work together to support how the brain functions. Glutathione plays a central role in maintaining Frontiers Glutathione: A Samsonian life sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation Dietary polyphenols and gutbrain axis modulation: the neuroprotective role of quercetin, allicin, and ferulic acid in traumatic brain injury and neurodegeneration ScienceDirect Glutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis Cell Death & Disease