When people think about detox, they usually think about the liver. But detoxification actually involves several systems working together. One of the most important is methylation. Methylation supports processes involved in Your blood tests are normal. Your sleep is adequate. You're still exhausted. This is the most common presentation I see in clinic and the answer is almost never found on a Redox methylation pathway Methionine synthase contains a redox active Download Scientific Diagram The methylation cycle and glutathione synthesis pathway. Metabolites Download Scientific Diagram