Frontiers Cysteine Depletion, a Key Action to Challenge Cancer Cells to Ferroptotic Cell Death Identification of cytotoxic, glutathione reactive moieties inducing accumulation of reactive oxygen species via glutathione depletion ScienceDirect Maturation of Cytosolic Iron Sulfur Proteins Requires Glutathione* Journal of Biological Chemistry The antioxidant glutathione protects against enteric neuron death in situ, but its depletion is protective during colitis American Journal of Physiology Gastrointestinal and Liver Physiology American Physiological Society
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depletion of glutathione Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells