COM March 2009 Diagnosis UW School of Dentistry Labial Melanotic Macules in Atopic Dermatitis: An Observational Study Semantic Scholar Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. a Melanotic macule at the wetdry line of the lower lip. b Melanotic Download Scientific Diagram