The use of HCT and or ACE inhibitors significantly increases the risk of non melanotic skin cancer in the periocular region Graefe's Archive for Clinical and Experimental Ophthalmology Springer Nature Link Nevus Nevi Concise Medical Knowledge Case Challenge! We have a 68 year old patient with no significant past medical history presenting for consultation. A progressively growing melanocytic lesion on the frontal region. Duration: Approximately 1 year. Symptoms: Non pruritic. How Can You Tell if It's Melanoma or Just a Mole?